CD27/CD70 interaction directly induces natural killer cell killing activity
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چکیده
منابع مشابه
Tumor-derived alpha fetoprotein directly impacts human natural killer cell activity and viability
Alpha-fetoprotein (AFP) is an oncofetal antigen produced by hepatocellular carcinomas (HCC). Previous studies demonstrated that tumor-derived AFP (tAFP) is a glycoprotein that has an immunosuppressive role on natural killer (NK), T, B, and dendritic (DC) cells which may play a role in HCC pathogenesis. Defects in NK cells have been attributed to tAFP-mediated immunosuppression of DC. However, a...
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ژورنال
عنوان ژورنال: Immunology
سال: 1996
ISSN: 0019-2805
DOI: 10.1111/j.1365-2567.1996.tb00017.x